Forster Jameson, Sarosiek Irene, Lin Zhiyue, Durham Sara, Denton Suzanne, Roeser Katherine, McCallum Richard W
Department of Surgery, Kansas University Medical Center, Kansas City 66160-7309, USA.
Am J Surg. 2003 Dec;186(6):690-5. doi: 10.1016/j.amjsurg.2003.08.024.
Gastric electrical stimulation (GES) has been introduced for patients with gastroparesis refractory to pharmacological therapy.
From April 1998 until November 2001, 55 patients underwent GES implantation at Kansas University Medical Center. All patients had prolonged gastric retention of a solid meal by scintigraphy at baseline. The etiologies were diabetes mellitus in 39, related to previous surgery in 9, and idiopathic in 7. Symptoms were graded using a 5-point scale and quality of life was assessed with the SF-36 questionnaire. Body mass index and nutritional parameters were monitored. Hemoglobin A1C was measured in the diabetic patients.
Total symptom scores and the physical and mental composite scores of quality of life improved significantly. On average, gastric emptying did not change. Body mass index and body weight increased significantly. And days spent in hospital admissions were significantly decreased. At 1 year, diabetic patients experienced reduced hemoglobin A1C. Four devices were removed. One patient died of a pulmonary embolus postoperatively.
In a large series of patients with gastroparesis, GES significantly improved symptoms and quality of life.
胃电刺激（GES）已被应用于药物治疗无效的胃轻瘫患者。
1998年4月至2001年11月，55例患者在堪萨斯大学医学中心接受了GES植入术。所有患者在基线时通过闪烁扫描显示固体餐胃潴留时间延长。病因包括糖尿病39例，既往手术相关9例，特发性7例。症状采用5分制评分，生活质量用SF-36问卷评估。监测体重指数和营养参数。对糖尿病患者测量糖化血红蛋白A1C。
总症状评分以及生活质量的身体和心理综合评分显著改善。平均而言，胃排空未发生变化。体重指数和体重显著增加。住院天数显著减少。1年后，糖尿病患者的糖化血红蛋白A1C降低。4台装置被移除。1例患者术后死于肺栓塞。
在一大系列胃轻瘫患者中，GES显著改善了症状和生活质量。
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