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二氧化碳气腹下内镜胸交感神经切断术中动态肺顺应性的变化

Variations in dynamic lung compliance during endoscopic thoracic sympathectomy with CO2 insufflation.

作者信息

El-Dawlatly Abdelazeem Ali, Al-Dohayan Abdullah, Abdel-Meguid Mohamed Essam, Turkistani Ahmed, Alotaiby Wadha Mubarak, Abdelaziz Emad Mansoor

机构信息

Dept. of Anesthesia, College of Medicine King Saud University, Riyadh, Saudia Arabia.

出版信息

Clin Auton Res. 2003 Dec;13 Suppl 1:I94-7. doi: 10.1007/s10286-003-1120-4.

Abstract

Endoscopic thoracic sympathectomy (ETS) is the preferred surgery for treatment of intractable palmar hyperhidrosis (PH). General anesthesia with onelung collapsed ventilation (OLCV) using single-lumen tracheal tube (SLT), is our preferred anesthetic technique for ETS. Intrapleural CO(2) insufflation (capnothorax) was used to ensure lung collapse. The current study examined the effects of capnothorax on dynamic lung compliance (DLC) of the ventilated lung during ETS. After obtaining written informed consent, 10 adult male patients ASA I&II undergoing ETS were studied. Their average age and weight were 25 +/- 7 yr and 67 +/- 8 kg. General anesthesia with SLT and OLCV technique was used. Capnothorax with intrapleural pressure (IPP) of 10 mmHg was initially used, then it was reduced and maintained at 5 mmHg throughout the operation. Anesthesia delivery unit (Datex Ohmeda type A_Elec, Promma, Sweden) was used where airway pressures and DLC were displayed during OLCV. A computer program (SPSS 9.0 for Windows; SPSS Inc., Chicago, IL) was used for statistical analysis of the data obtained. One way analysis of variance (ANOVA) was used for analysis of data before, during and after OLCV. P<0.05 was considered significant. The mean values of the DLC were 52 +/- 6, 30 +/- 3, 39 +/- 5 and 53 +/- 9 ml/cmH(2)O before, during (at 10 and 5 mmHg IPP) and after OLCV respectively with significant differences before and at 10 and 5mmHg IPP. In conclusions, during OLCV and capnothorax for ETS, DLC tends to decrease with increasing of intrapleural CO(2) insufflation pressure. However, in short procedures it has no deleterious postoperative effect. To the best of our knowledge this is the first study performed to investigate DLC changes during OLCV with capnothorax.

摘要

内镜胸交感神经切断术(ETS)是治疗顽固性手掌多汗症(PH)的首选手术。使用单腔气管导管(SLT)进行单肺萎陷通气(OLCV)的全身麻醉是我们进行ETS手术时首选的麻醉技术。采用胸膜腔内二氧化碳充气(二氧化碳气胸)来确保肺萎陷。本研究探讨了二氧化碳气胸对ETS手术期间通气肺动态肺顺应性(DLC)的影响。在获得书面知情同意后,对10例接受ETS手术的ASA I&II级成年男性患者进行了研究。他们的平均年龄和体重分别为25±7岁和67±8千克。采用SLT和OLCV技术进行全身麻醉。最初使用胸膜腔内压力(IPP)为10mmHg的二氧化碳气胸,然后在整个手术过程中将其降至并维持在5mmHg。使用麻醉输送装置(瑞典Promma公司的Datex Ohmeda A_Elec型),在OLCV期间显示气道压力和DLC。使用计算机程序(适用于Windows的SPSS 9.0;SPSS公司,伊利诺伊州芝加哥)对获得的数据进行统计分析。采用单因素方差分析(ANOVA)对OLCV之前、期间和之后的数据进行分析。P<0.05被认为具有统计学意义。DLC的平均值在OLCV之前、期间(IPP为10和5mmHg时)和之后分别为52±6、30±3、39±5和53±9ml/cmH₂O,在IPP为10和5mmHg时与之前有显著差异。结论是,在ETS的OLCV和二氧化碳气胸过程中,DLC倾向于随着胸膜腔内二氧化碳充气压力的增加而降低。然而,在短时间手术中,它没有有害的术后影响。据我们所知,这是第一项研究OLCV联合二氧化碳气胸期间DLC变化的研究。

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