Madan S S, Boeree N R
Southampton University, Southampton, UK.
Eur Spine J. 2003 Dec;12(6):567-75. doi: 10.1007/s00586-002-0516-5. Epub 2003 Aug 28.
Posterior lumbar interbody fusion (PLIF) restores disc height, the load bearing ability of anterior ligaments and muscles, root canal dimensions, and spinal balance. It immobilizes the painful degenerate spinal segment and decompresses the nerve roots. Anterior lumbar interbody fusion (ALIF) does the same, but could have complications of graft extrusion, compression and instability contributing to pseudarthrosis in the absence of instrumentation. The purpose of this study was to assess and compare the outcome of instrumented circumferential fusion through a posterior approach [PLIF and posterolateral fusion (PLF)] with instrumented ALIF using the Hartshill horseshoe cage, for comparable degrees of internal disc disruption and clinical disability. It was designed as a prospective study, comparing the outcome of two methods of instrumented interbody fusion for internal disc disruption. Between April 1994 and June 1998, the senior author (N.R.B.) performed 39 instrumented ALIF procedures and 35 instrumented circumferential fusion with PLIF procedures. The second author, an independent assessor (S.M.), performed the entire review. Preoperative radiographic assessment included plain radiographs, magnetic resonance imaging (MRI) and provocative discography in all the patients. The outcome in the two groups was compared in terms of radiological improvement and clinical improvement, measured on the basis of improvement of back pain and work capacity. Preoperatively, patients were asked to fill out a questionnaire giving their demographic details, maximum walking distance and current employment status in order to establish the comparability of the two groups. Patient assessment was with the Oswestry Disability Index, quality of life questionnaire (subjective), pain drawing, visual analogue scale, disability benefit, compensation status, and psychological profile. The results of the study showed a satisfactory outcome (score< or =30) on the subjective (quality of life questionnaire) score of 71.8% (28 patients) in the ALIF group and 74.3% (26 patients) in the PLIF group (P>0.05). On categorising Oswestry Index scores into "excellent", "better", "same", and "worse", we found no difference in outcome between the two groups: 79.5% (n=31) had satisfactory outcome with ALIF and 80% (n=28) had satisfactory outcome with PLIF. The rate of return to work was no different in the two groups. On radiological assessment, we found two nonunions in the circumferential fusion (PLIF) group (94.3% fusion rate) and indirect evidence of no nonunions in the ALIF group. There was no significant difference between the compensation rate and disability benefit rate between the two groups. There were three complications in ALIF group and four in the PLIF (circumferential) group. On the basis of these results, we conclude that it is possible to treat discogenic back pain by anterior interbody fusion with Hartshill horseshoe cage or with circumferential fusion using instrumented PLIF.
腰椎后路椎间融合术(PLIF)可恢复椎间盘高度、前纵韧带和肌肉的承重能力、根管尺寸以及脊柱平衡。它能固定疼痛的退变脊柱节段并减压神经根。腰椎前路椎间融合术(ALIF)也有同样作用,但在未使用内固定器械时,可能会出现植骨块挤出、受压及不稳定等并发症,进而导致假关节形成。本研究的目的是评估并比较采用后路入路的器械辅助环形融合术(PLIF和后外侧融合术(PLF))与使用Hartshill马蹄形椎间融合器的器械辅助ALIF治疗程度相当的椎间盘内部破裂及临床功能障碍的疗效。本研究设计为前瞻性研究,比较两种器械辅助椎间融合术治疗椎间盘内部破裂的疗效。1994年4月至1998年6月期间,资深作者(N.R.B.)实施了39例器械辅助ALIF手术和35例采用PLIF手术的器械辅助环形融合术。第二作者,一名独立评估者(S.M.)进行了全部评估工作。术前影像学评估包括所有患者的X线平片、磁共振成像(MRI)和激发性椎间盘造影。根据背痛改善情况和工作能力,比较两组患者在影像学改善和临床改善方面的疗效。术前,要求患者填写一份问卷,提供其人口统计学细节、最大步行距离和当前就业状况,以确定两组的可比性。采用Oswestry功能障碍指数、生活质量问卷(主观)、疼痛绘图、视觉模拟评分、残疾福利、赔偿状况和心理状况对患者进行评估。研究结果显示ALIF组主观(生活质量问卷)评分的满意度(评分≤30)为71.8%(28例患者),PLIF组为74.3%(26例患者)(P>0.05)。将Oswestry指数评分分为“优秀”、“较好”、“相同”和“较差”,我们发现两组疗效无差异:ALIF组79.5%(n = 31)疗效满意,PLIF组80%(n = 28)疗效满意。两组的重返工作率无差异。影像学评估发现环形融合(PLIF)组有2例骨不连(融合率94.3%),ALIF组无骨不连的间接证据。两组的赔偿率和残疾福利率无显著差异。ALIF组有3例并发症,PLIF(环形)组有4例并发症。基于这些结果,我们得出结论,采用Hartshill马蹄形椎间融合器进行前路椎间融合术或采用器械辅助PLIF进行环形融合术治疗椎间盘源性背痛都是可行的。