Maly Bella, Maly Alexander, Doviner Victoria, Reinhartz Toby, Sherman Yoav
Department of Pathology, Jerusalem Hadassah University Hospital, Kiryat Hadassah, P.O. Box 12000, il-91120, Jerusalem, Israel.
Acta Cytol. 2003 Nov-Dec;47(6):1131-4. doi: 10.1159/000326664.
Intraparotid schwannoma of the salivary gland is a rare entity. Review of the literature revealed one previous report describing its cytologic features.
A 22-year-old man had a slowly growing, painless mass in the left parotid gland. Fine needle aspiration biopsy, performed prior to surgical excision, showed several tissue fragments consisting of uniform, spindle-shaped neoplastic cells with cigar-shaped nuclei and scant, ill-defined cytoplasm. Some of the neoplastic cells were clustered in typical arrangements of Verocay bodies. In addition, lymphocytes and foamy histiocytes were found. A diagnosis of schwannoma was made. Pathologic evaluation of the resected parotid mass supported the diagnosis.
The diagnosis of intraparotid schwannoma can be made by examining cytologic material containing the characteristic Verocay bodies. The correct cytologic diagnosis of this entity helps to rule out morphologically similar primary salivary gland neoplasms and thereby permits the appropriate surgical procedure to ensue.
腮腺内涎腺神经鞘瘤是一种罕见的疾病。文献回顾显示之前有一篇报告描述了其细胞学特征。
一名22岁男性左侧腮腺有一个生长缓慢、无痛性肿块。在手术切除前进行的细针穿刺活检显示有几个组织碎片，由形态一致的梭形肿瘤细胞组成，细胞核呈雪茄状，细胞质稀少且界限不清。一些肿瘤细胞聚集成典型的Verocay小体结构。此外，还发现了淋巴细胞和泡沫状组织细胞。诊断为神经鞘瘤。对切除的腮腺肿块进行的病理评估支持该诊断。
通过检查含有特征性Verocay小体的细胞学材料可诊断腮腺内神经鞘瘤。对该疾病做出正确的细胞学诊断有助于排除形态学上相似的原发性涎腺肿瘤，从而能够采取适当的手术方法。
