Fyrmpas G, Konstantinidis I, Hatzibougias D, Vital V, Constantinidis J
Department of Otolaryngology Head and Neck Surgery, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
Eur Arch Otorhinolaryngol. 2008 Jun;265(6):699-703. doi: 10.1007/s00405-007-0521-8.
Intraparotid facial nerve schwannoma (FNS) is a very rare, benign tumour mimicking pleomorphic adenoma. Resection of this slow growing tumour may result in unnecessary facial nerve paralysis. The aim of this study is to present results of facial nerve schwannoma treatment at our institution and proposes a management plan. This is a retrospective case series of four patients, three male and one female with a mean age of 47.7 years who presented with a long-standing, asymptomatic parotid swelling. Two patients had facial weakness and underwent superficial parotidectomy, resection of tumour and facial nerve repair with a free graft from the greater auricular nerve. Two patients underwent biopsy without tumour resection. All tumours were confirmed histologically as facial nerve schwannomas. The mean follow up period was 3.5 years. Patients with resection of facial nerve schwannoma had a postoperative House Brackmann grade III and IV. Patients with biopsy had normal postoperative facial nerve function and the tumour did not grow significantly. No adverse effects or recurrence were reported. There is no preoperative diagnostic modality that can identify facial nerve schwannoma with certainty. Difficulty in locating the facial nerve intraoperatively raises suspicion of a neurogenous tumour of the facial nerve and this may prevent unnecessary damage to the nerve. Not every facial nerve schwannoma should be resected. This decision is based on (a) the extent of tumour (b) preoperative facial nerve function (c) best results achieved with nerve repair and (d) patient's preferences. Large tumours with extension into the mastoid cavity or encroachment of sensitive structures and preoperative facial weakness are indications for surgical intervention. In most other cases, biopsy and observation suffices.
腮腺内面神经鞘瘤(FNS)是一种非常罕见的良性肿瘤,酷似多形性腺瘤。切除这种生长缓慢的肿瘤可能导致不必要的面神经麻痹。本研究的目的是展示我们机构治疗面神经鞘瘤的结果并提出一个管理方案。这是一个回顾性病例系列,包括4例患者,3例男性和1例女性,平均年龄47.7岁,均表现为长期无症状的腮腺肿胀。2例患者有面部无力,接受了浅叶腮腺切除术、肿瘤切除及用耳大神经游离移植进行面神经修复。2例患者接受了活检但未进行肿瘤切除。所有肿瘤经组织学确诊为面神经鞘瘤。平均随访期为3.5年。切除面神经鞘瘤的患者术后House Brackmann分级为III级和IV级。接受活检的患者术后面神经功能正常,肿瘤无明显生长。未报告有不良反应或复发情况。目前尚无术前诊断方法能确切识别面神经鞘瘤。术中定位面神经困难会增加对面神经神经源性肿瘤的怀疑,这可能避免对面神经造成不必要的损伤。并非每个面神经鞘瘤都应切除。这一决定基于(a)肿瘤范围(b)术前面神经功能(c)神经修复所能达到的最佳效果以及(d)患者的偏好。肿瘤较大且延伸至乳突腔或侵犯敏感结构以及术前存在面部无力是手术干预的指征。在大多数其他情况下,活检和观察就足够了。