[The state of lipid peroxidation and of the antioxidant system in the liver and lung microsomes at different periods of sensitization depending on the histamine content].

Histamine impact on lipid peroxidation (LPO) in hepatic and pulmonary microsomes of guinea-pigs sensibilization was studied. It is demonstrated that intensity of chemiluminescence and LPO product content in NADPH-, ascorbat-dependent and spontaneous systems was enhanced in relation to the period of sensibilization process formation and histamine concentration.