Law Simon, Wong John
Division of Esophageal Surgery, Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong.
J Gastroenterol Hepatol. 2004 Jan;19(1):4-12. doi: 10.1111/j.1440-1746.2004.03154.x.
Options for the treatment of esophageal cancer used to be very limited, with surgical resection and radiotherapy methods aimed at both cure or palliation, and, in those unfortunate patients with severe dysphagia, intubation with a plastic prosthesis to restore esophageal luminal patency. Progress in the management of this cancer in the past two decades includes refinement in surgical techniques and perioperative care, better radiological staging methods, enhanced means of planning and delivering radiotherapy, multimodality treatments, and better designs in esophageal prosthesis. For individual patients, a stage-directed therapeutic plan can be used. Long-term survival, however, remains suboptimal for this deadly disease. The current review presents an overview of the commonly employed therapeutic options for esophageal cancer at the beginning of the 21st century.
过去，食管癌的治疗选择非常有限，手术切除和放射治疗方法旨在治愈或缓解症状，对于那些吞咽困难严重的不幸患者，则采用插入塑料假体以恢复食管腔通畅。在过去二十年中，这种癌症的治疗进展包括手术技术和围手术期护理的改进、更好的放射学分期方法、增强的放疗计划和实施手段、多模式治疗以及食管假体的更好设计。对于个体患者，可以采用分阶段的治疗方案。然而，对于这种致命疾病，长期生存率仍然不尽人意。本综述概述了21世纪初食管癌常用的治疗选择。
