Heart, Lung & Esopahgeal Surgery Institute, University of Pittsburgh Medical Center, C-800 PUH, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Int J Surg. 2010;8(6):417-22. doi: 10.1016/j.ijsu.2010.06.011. Epub 2010 Jun 30.
Esophageal cancer continues to be a lethal disease with the majority of patients presenting at an advanced stage. The incidence of adenocarcinoma is rising. Although Barrett's esophagus has been well characterized, specific pathways to the development of adenocarcinoma remain undefined. Current treatments for locoregional esophageal cancer include surgery, chemotherapy, radiation therapy, or a combination of these modalities. Optimal surgical treatment strategies include appropriate patient selection, accurate staging and risk assessment, selection of an appropriate surgical approach, and the use of multimodality treatment. This article provides an update on the myriad of options for managing esophageal cancer and outlines the surgical technique for minimally invasive esophagectomy used at our center.
食管癌仍然是一种致命疾病,大多数患者就诊时已处于晚期。腺癌的发病率正在上升。尽管 Barrett 食管的特征已经得到很好的描述,但腺癌发展的确切途径仍不清楚。局部晚期食管癌的当前治疗包括手术、化疗、放疗或这些方法的联合应用。最佳的手术治疗策略包括适当的患者选择、准确的分期和风险评估、选择合适的手术方法以及多模式治疗的应用。本文提供了食管癌多种治疗方法的最新信息,并概述了我们中心使用的微创食管切除术的手术技术。