一名年轻女性因子宫内膜异位症引发的卵巢子宫内膜样腺癌。
Ovarian endometrioid adenocarcinoma arising from endometriosis in a young woman.
作者信息
Tagashira Yukiko, Shimada Muneaki, Kigawa Junzo, Iba Takahiro, Terakawa Naoki
机构信息
Department of Obstetrics and Gynecology, Tottori University School of Medicine, 36-1 Nishimachi Yonago, 6838504, Japan.
出版信息
Gynecol Oncol. 2003 Dec;91(3):643-7. doi: 10.1016/j.ygyno.2003.08.005.
BACKGROUND
The risk of ovarian cancer increases in women with a long history of ovarian endometriosis, particularly in postmenopausal women. We present here a case of malignant transformation of endometriosis occurring over a short time in a young woman.
CASE
The 27-year-old woman underwent laparoscopic cystectomy and was diagnosed with left ovarian endometrioma with an accompanying high level of serum CA125 (734.6 U/mL). Fourteen months later, she underwent cytoreductive surgery for her ovarian cancer. Histological examination revealed endometrioid adenocarcinoma with transitions between endometriosis and adenocarcinoma. She was diagnosed as having stage IIIc of ovarian cancer with paraaortic lymphnode involvement.
CONCLUSION
We suggest that endometrial cyst of the ovary associated with high levels of serum CA125 should be managed with special care even in a young woman.
背景
卵巢子宫内膜异位症病史较长的女性，尤其是绝经后女性，患卵巢癌的风险会增加。我们在此介绍一名年轻女性在短时间内发生子宫内膜异位症恶变的病例。
病例
这名27岁的女性接受了腹腔镜囊肿切除术，被诊断为左卵巢子宫内膜异位囊肿，同时血清CA125水平较高（734.6 U/mL）。14个月后，她因卵巢癌接受了肿瘤细胞减灭术。组织学检查显示为子宫内膜样腺癌，伴有子宫内膜异位症与腺癌之间的过渡。她被诊断为卵巢癌Ⅲc期，伴有腹主动脉旁淋巴结受累。
结论
我们建议，即使是年轻女性，对于伴有血清CA125水平升高的卵巢子宫内膜囊肿也应特别谨慎处理。
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