Orlova N P, Volodin E E, Lokhvitskaia N L
Kardiologiia. 1978 Jan;18(1):115-8.
Complex study of blood platelet adhesion and aggregation, blood coagulation activity and oxidation-reduction processes was conducted in dynamics in 340 patients with myocardial infarction. in 53 of them before and after treatment with fibrinolysin and heparin. It is shown that in patients with myocardial infarction, particularly in the first days of the disease and with the development of cardiogenic shock and pulmonary edema, the adhesion and aggregation of blood platelets increase with parallel increase in the content of incompletely oxidized products in the blood. A definite parallelism was found between the changes in the kinetic properties of platelets and the oxidoreduction processes. A decrease in the platelet kinetic properties and improvement in the oxidation-reduction processes due to the effect of fibrinolysin and heparin were observed.
对340例心肌梗死患者的血小板黏附与聚集、凝血活性及氧化还原过程进行了动态综合研究。其中53例在使用纤维蛋白溶酶和肝素治疗前后进行了研究。结果表明，在心肌梗死患者中，尤其是在疾病的最初几天以及发生心源性休克和肺水肿时，血小板的黏附与聚集增加，同时血液中不完全氧化产物的含量也平行增加。发现血小板动力学特性的变化与氧化还原过程之间存在一定的平行关系。观察到由于纤维蛋白溶酶和肝素的作用，血小板动力学特性降低，氧化还原过程得到改善。
