Atlan D, Chevallier B
Service d'oncologie médicale, centre Henri-Becquerel, Rouen, France.
Bull Cancer. 1992;79(7):659-66.
The neuroendocrine carcinomas of the skin, also called Merkel cell carcinomas, are unusual malignancies mostly observed in the elderly. They are diagnosed by a pathologist: ultrastructural studies and immunohistochemistry support the diagnosis. The prognosis is poor. Lymph nodes and metastases quickly arise although sometimes, they are discovered immediately. A combination of surgery and radiotherapy is recommended. Metastases and unresectable tumors should be treated by chemotherapy.
皮肤神经内分泌癌，也称为默克尔细胞癌，是一种罕见的恶性肿瘤，多见于老年人。由病理学家进行诊断：超微结构研究和免疫组织化学有助于确诊。预后较差。尽管有时会立即被发现，但淋巴结转移很快就会出现。建议采用手术和放疗相结合的治疗方法。转移瘤和无法切除的肿瘤应采用化疗。
