Bassereau G, Manceau A, Soin C, Maitre F, Breteau N
Centre Hospitalier Régional d'Orléans, Fleury les Aubrais.
Ann Otolaryngol Chir Cervicofac. 1995;112(3):123-8.
The clinical and pathological features of 4 cases of cutaneous neuroendocrine carcinoma are reported. There are unusual malignancies mostly observed in elderly, the prognosis is poor by loco-regional aggressivity and disseminated metastases. They are diagnosed by a pathologist: ultrastructural studies and immunohistochemistry support the diagnosis. A combination of a wild local excision, node dissection and post-operative radiation is recommended.
报告了4例皮肤神经内分泌癌的临床和病理特征。这些是不常见的恶性肿瘤，多见于老年人，因局部侵袭性和远处转移而预后较差。由病理学家进行诊断：超微结构研究和免疫组织化学支持该诊断。建议采用广泛局部切除、淋巴结清扫和术后放疗相结合的治疗方法。
