Grabec Igor, Groselj Dusan
Faculty of Mechanical Engineering, University of Ljubljana, Askerceva c. 6, POB 394 1000, Slovenia.
Comput Methods Biomech Biomed Engin. 2003 Oct-Dec;6(5-6):319-28. doi: 10.1080/10255840310001635006.
The focus of the article is on a generic approach to prediction of a healing process based on automatic measurement and modelling of mechanical disease indicators. As a specific example the healing process after treatment of advanced periodontitis is characterised and predicted based on measurement of tooth mobility (TM). For the measurement a new mechatronic instrument was developed that includes a pneumatically driven probe with incorporated sensors of tooth displacement and loading force. TM is measured by a computer controlled data acquisition system and predicted by a non-parametric regression. Similarly as in the characterisation of technical processes, a measured sample is described by TM time series detected on a particular patient, while the regression is determined by a set of samples obtained from a group of patients following periodontal therapy. The influence of surgical access therapy and systemic administration of metronidazole as an adjunct to the mechanical treatment is demonstrated. For this purpose the average changes of tooth mobility are determined on variously treated subgroups. A new method of healing process prediction is demonstrated and its performance is described by a prediction quality.
本文的重点是一种基于机械性疾病指标的自动测量和建模来预测愈合过程的通用方法。作为一个具体例子,基于牙齿动度(TM)的测量,对晚期牙周炎治疗后的愈合过程进行了表征和预测。为了进行测量,开发了一种新型机电一体化仪器,该仪器包括一个气动驱动的探头,内置了牙齿位移和加载力传感器。TM由计算机控制的数据采集系统测量,并通过非参数回归进行预测。与技术过程的表征类似,通过在特定患者身上检测到的TM时间序列来描述测量样本,而回归则由一组接受牙周治疗的患者获得的样本确定。展示了手术入路治疗和甲硝唑全身给药作为机械治疗辅助手段的影响。为此,在不同治疗的亚组中确定了牙齿动度的平均变化。展示了一种新的愈合过程预测方法,并通过预测质量描述了其性能。