Fahal A H, Hassan M A
Department of Surgery, Faculty of Medicine, University of Khartoum, Sudan.
Br J Surg. 1992 Nov;79(11):1138-41. doi: 10.1002/bjs.1800791107.
Mycetoma is a chronic infective condition of tropical and subtropical regions. It is commoner in males, especially those in their third or fourth decade who work on the land. The clinical triad of subcutaneous nodule, sinuses and discharge usually leads to diagnosis; the disease is commonly painless. Treatment is by extensive surgical excision of affected areas and may include limb amputation. Recurrence is common, rates ranging from 20 to 90 per cent. Medical treatment may be used on its own or as an adjunct to surgery. Although such therapy may cure over half of those with actinomycetoma (caused by bacteria, mainly aerobic actinomycetes), those affected by eumycetoma (caused by fungi) have a poorer prognosis and may require many years of drug therapy.
足菌肿是热带和亚热带地区的一种慢性感染性疾病。男性更为常见，尤其是那些三四十岁从事农业劳动的男性。皮下结节、窦道和分泌物这一临床三联征通常可导致诊断；该病通常无痛。治疗方法是广泛手术切除受影响区域，可能包括截肢。复发很常见，复发率在20%至90%之间。药物治疗可单独使用或作为手术辅助手段。尽管这种疗法可能治愈超过一半的放线菌性足菌肿患者（由细菌引起，主要是需氧放线菌），但受真菌性足菌肿（由真菌引起）影响的患者预后较差，可能需要多年的药物治疗。
