Lai Chih-Cheng, Teng Lee-Jene, Hsueh Po-Ren, Yuan Ang, Tsai Kuang-Chau, Tang Jih-Luh, Tien Hwei-Fang
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Clin Infect Dis. 2004 Jan 1;38(1):149-53. doi: 10.1086/380463. Epub 2003 Dec 4.
Data obtained from 1996 to 2002 on 13 patients with Rhizobium radiobacter infections were analyzed. Ten patients (76%) had underlying hematological malignancy or solid-organ cancer. Six patients (46%) had febrile neutropenia during the course of R. radiobacter infection. The majority (54%) of infections were catheter-related bacteremia, and 92% of infections were hospital acquired. All the patients survived. Eighteen isolates were recovered from the 13 patients, and each isolate was susceptible to cefepime, piperacillin-tazobactam, carbapenems, and ciprofloxacin. The pulsed-field gel electrophoresis profiles differed among the isolates recovered from different patients, indicating the absence of nosocomial spread of the organism.
对1996年至2002年期间13例放射型根瘤菌感染患者的数据进行了分析。10例患者(76%)患有潜在血液系统恶性肿瘤或实体器官癌症。6例患者(46%)在放射型根瘤菌感染过程中出现发热性中性粒细胞减少。大多数感染(54%)为导管相关菌血症,92%的感染为医院获得性。所有患者均存活。从13例患者中分离出18株菌株,每株菌株对头孢吡肟、哌拉西林-他唑巴坦、碳青霉烯类和环丙沙星敏感。从不同患者分离出的菌株脉冲场凝胶电泳图谱不同,表明该菌没有医院内传播。