Bacterial endophthalmitis with lens capsule rupture and retinal detachment: A case report of infection.

PURPOSE

To report our findings in a rare case of unilateral endophthalmitis caused by in a healthy young man complicated by a rupture of the lens capsule and a rhegmatogenous retinal detachment (RRD).

OBSERVATIONS

A 22-year-old Cambodian man presented with recurrent blurry vision in the left eye, following a two-year history of recurrent uveitis initially responsive to corticosteroid treatment. However, during the second recurrence, corticosteroids failed to control the inflammation. At our initial examination, non-granulomatous keratic precipitates, posterior synechiae, and vitreous opacities were observed. Polymerase chain reaction (PCR) of the aqueous humor identified bacterial DNA leading to a suspicion of bacterial endophthalmitis. Vitreous surgery revealed a lens capsule rupture and a giant retinal tear. Retinal photocoagulation and silicone oil tamponade were performed to reattach the retina. Given his occupation at a construction site, ocular trauma was considered. However, preoperative examination and intraoperative findings revealed no evidence of intraocular foreign bodies. Cultures of the vitreous fluid detected . Targeted antibiotic therapy with topical levofloxacin and systemic ciprofloxacin was administered, and the decimal best-corrected visual acuity improved to 1.2 two months post-treatment.

IMPORTANCE AND CONCLUSION

This case highlights the diagnostic and therapeutic challenges posed by rare pathogens such as . Clinicians should be aware of bacterial causes in atypical uveitis particularly in patients refractory to conventional therapy.