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猫正常和轴突切断的面神经运动神经元的形态学与电生理特性观察

Observations on morphology and electrophysiological properties of the normal and axotomized facial motoneurons in the cat.

作者信息

Nishimura Y, Asahara T, Yamamoto T, Tanaka T

机构信息

Department of Physiology, School of Medicine, Mie University, Mie-ken, Japan.

出版信息

Brain Res. 1992 Nov 20;596(1-2):305-10. doi: 10.1016/0006-8993(92)91562-s.

DOI:10.1016/0006-8993(92)91562-s
PMID:1467993
Abstract

The correlation between the morphology of facial motoneurons stained intracellularly with horseradish peroxidase and their physiological parameters was examined in cats following facial nerve section and in cats with intact facial nerve. A certain statistical relationship exists between cell size and excitability in normal neurons. After axotomy, facial neurons showed a slow conduction velocity and a low rheobasic current, but had a normal cell size. Physiological changes include repetitive firing in response to intracellular current injection, reflecting an increase in the excitability in the axotomized neurons.

摘要

在面神经切断后的猫以及面神经完整的猫中,研究了用辣根过氧化物酶进行细胞内染色的面运动神经元形态与其生理参数之间的相关性。正常神经元的细胞大小与兴奋性之间存在一定的统计关系。轴突切断后,面神经元传导速度减慢,基强度电流降低,但细胞大小正常。生理变化包括对细胞内电流注入产生重复放电,这反映了轴突切断的神经元兴奋性增加。

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