Introducing the concept of breast cancer stem cells.
作者信息
Waterworth Alison
机构信息
Molecular Medicine Unit, Clinical Sciences Building, St James's University Hospital, Leeds, UK.
出版信息
Breast Cancer Res. 2004;6(1):53-4. doi: 10.1186/bcr749. Epub 2003 Nov 20.
Abstract
摘要
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PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells.PC3人前列腺癌细胞全克隆包含自我更新的肿瘤起始细胞。
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Breast cancer stem cells: an overview.乳腺癌干细胞：概述
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Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells.转移性乳腺癌细胞的乳腺球培养可富集致瘤性乳腺癌细胞。
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Presence of apoptotic and nonapoptotic disseminated tumor cells reflects the response to neoadjuvant systemic therapy in breast cancer.凋亡和非凋亡播散肿瘤细胞的存在反映了乳腺癌对新辅助全身治疗的反应。
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本文引用的文献
1
Prospective identification of tumorigenic breast cancer cells.致瘤性乳腺癌细胞的前瞻性鉴定。
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3983-8. doi: 10.1073/pnas.0530291100. Epub 2003 Mar 10.
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Stem cells, cancer, and cancer stem cells.干细胞、癌症与癌症干细胞。
Nature. 2001 Nov 1;414(6859):105-11. doi: 10.1038/35102167.
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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell.人类急性髓系白血病是由一个原始造血细胞起源的层级结构组成。
Nat Med. 1997 Jul;3(7):730-7. doi: 10.1038/nm0797-730.
4
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice.一种在移植到重症联合免疫缺陷（SCID）小鼠体内后引发人类急性髓系白血病的细胞。
Nature. 1994 Feb 17;367(6464):645-8. doi: 10.1038/367645a0.
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