马基亚法瓦-比尼亚米病：胼胝体和皮质下白质的磁共振成像表现

Marchiafava-Bignami disease: magnetic resonance imaging findings in corpus callosum and subcortical white matter.

作者信息

Kawarabuki Kentaro, Sakakibara Takehiko, Hirai Makoto, Yoshioka Yuji, Yamamoto Yasumasa, Yamaki Tarumi

机构信息

Department of Neurosurgery, Kyoto Kujo Hospital, Karahashi Rajomoncho 10, Minamiku, Kyoto 601-8453, Japan.

出版信息

Eur J Radiol. 2003 Nov;48(2):175-7. doi: 10.1016/S0720-048X(02)00349-2.

DOI:10.1016/S0720-048X(02)00349-2

PMID:14680909

Abstract

A case of Marchiafava-Bignami disease (MBD) is presented using magnetic resonance imaging (MRI). A patient with a long history of alcoholism developed a gait disturbance with involuntary movements at the lower extremities. MRI scans taken at the onset showed no particular abnormalities. He progressed to a coma 10 days later. MRI scans taken 20 days after the onset showed a focal lesion at the genu of the corpus callosum and he was diagnosed as having MBD. In addition, multiple lesions were observed in bilateral frontoparietal subcortical white matter. These lesions demonstrated similar intense MRI signals as the corpus callosum.

摘要

本文报告了一例使用磁共振成像（MRI）诊断的马奇亚法瓦-比尼亚米病（MBD）病例。一名有长期酗酒史的患者出现步态障碍及下肢不自主运动。发病初期的MRI扫描未显示出特定异常。10天后他陷入昏迷。发病20天后的MRI扫描显示胼胝体膝部有局灶性病变，他被诊断为患有MBD。此外，在双侧额顶叶皮质下白质中观察到多个病变。这些病变在MRI上显示出与胼胝体相似的高强度信号。