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急性马基亚法瓦-比尼亚米病:皮质和胼胝体受累的扩散加权磁共振成像

Acute Marchiafava-Bignami disease: diffusion-weighted MRI in cortical and callosal involvement.

作者信息

Ihn Yon Kwon, Hwang Seong Su, Park Young Ha

机构信息

Department of Radiology, St Vincent Hospital, The Catholic University of Korea, 93-6 Ji-Dong, Paldal-Gu, Suwon-Si, Gyenggi-Do, Korea.

出版信息

Yonsei Med J. 2007 Apr 30;48(2):321-4. doi: 10.3349/ymj.2007.48.2.321.

DOI:10.3349/ymj.2007.48.2.321
PMID:17461534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2628118/
Abstract

Marchiafava-Bignami disease (MBD) is a fatal disorder characterized by demyelination of the corpus callosum. MRI, suggestive of corpus callosum demyelination with associated white matter involvement in both cerebral hemispheres, indicates a diagnosis of MBD. In this case, MR diffusion-weighted findings taken at an acute stage of MBD revealed lesions not only in the corpus callosum but also in the cerebral cortex. Lower apparent diffusion coefficient values of the corpus callosum and cortical lesions were associated with poor clinical outcome.

摘要

马奇亚法瓦-比尼亚米病(MBD)是一种以胼胝体脱髓鞘为特征的致命性疾病。MRI提示胼胝体脱髓鞘并伴有双侧大脑半球白质受累,这表明可诊断为MBD。在该病例中,MBD急性期的磁共振扩散加权成像结果显示,病变不仅存在于胼胝体,还存在于大脑皮层。胼胝体和皮层病变的表观扩散系数值较低与临床预后不良相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/b05f4380c655/ymj-48-321-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/57149ebaff00/ymj-48-321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/21942c02275c/ymj-48-321-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/b05f4380c655/ymj-48-321-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/57149ebaff00/ymj-48-321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/21942c02275c/ymj-48-321-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1971/2628118/b05f4380c655/ymj-48-321-g003.jpg

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