[暴露于高能加速粒子和伽马射线辐射的大鼠发生乳腺肿瘤风险的比较]
[Comparison of risk of mammary tumors developing in rats exposed to high-energy accelerated particles and gamma-ray radiation].
作者信息
Fedorenko B S, Turusov V S
机构信息
State Research Center of the Russian Federation-Research Institute of Medico-Biological Problems, Russian Academy of Medical Sciences, Moscow.
出版信息
Vopr Onkol. 2003;49(5):623-9.
The frequency of tumorigenesis was investigated in the mammary glands of noninbred female rats and Wistar rats, after total-body exposure to a single dose of 60CO gamma radiation, 645 MeV and 9 GeV protons and 4 GeV/nuclon ions of helium. It was found that the relative biological effects of accelerated charged particles was significantly higher. This finding was obtained from calculations of the frequency of mammary tumors.
在非近交系雌性大鼠和Wistar大鼠的乳腺中，研究了全身单次暴露于60Coγ射线、645兆电子伏特和9吉电子伏特质子以及4吉电子伏特/核子的氦离子后的肿瘤发生频率。结果发现，加速带电粒子的相对生物学效应显著更高。这一发现是通过计算乳腺肿瘤的发生频率得出的。
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