[Nonparametric method of determining the RBE coefficients of accelerated charged particles by the incidence of neoplasms in rats].

The nonparametric method was used to determine RBE coefficients of accelerated charged particles (helium ions of 4 GeV/nucleon and 645 MeV protons) by the incidence of tumors localized in different rat organs or by the absence of tumors. The nonparametric method permitted to find the dose dependence of the RBE coefficients and to make statistical analysis of the results obtained with due regard for come features of developing damages which were not revealed by conventional methods of determining RBE coefficients.