Hanau C A, Chancellor M B, Alexander A, Rishi M, Jordan A G
Department of Pathology and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, PA 19107.
Diagn Cytopathol. 1992;8(6):614-6. doi: 10.1002/dc.2840080616.
Periurethral Teflon injections are being used increasingly for the treatment of urinary incontinence after radical prostatectomy. We report a case of a man who developed increasing obstructive urinary symptoms and stress incontinence following radical retropubic prostatectomy. Six months earlier, he had undergone periurethral Teflon injections. On transrectal ultrasound and magnetic resonance imaging, a 3.2-cm cystic lesion was noted at the prostatic bed near the bladder neck where the Teflon had been injected. Ultrasound-guided transperineal fine-needle aspiration of the cyst yielded a specimen with numerous birefringent crystalline Teflon particles. Although previous reports have described granulomatous tissue reaction, no multinucleated giant cells were present to suggest granuloma formation. To our knowledge, this is the first reported case of Teflon cyst formation following periurethral Teflon injections. The patient's history, imaging studies, cytopathology, and review of the literature are presented in this report.
尿道周围注射聚四氟乙烯越来越多地用于根治性前列腺切除术后尿失禁的治疗。我们报告一例男性患者，他在耻骨后根治性前列腺切除术后出现进行性加重的排尿梗阻症状和压力性尿失禁。6个月前，他接受了尿道周围聚四氟乙烯注射。经直肠超声和磁共振成像显示，在膀胱颈附近的前列腺床处，即曾注射聚四氟乙烯的部位，发现一个3.2厘米的囊性病变。超声引导下经会阴对囊肿进行细针穿刺抽吸，获得的标本中有大量双折射结晶状聚四氟乙烯颗粒。尽管先前的报告描述了肉芽肿组织反应，但未发现多核巨细胞提示肉芽肿形成。据我们所知，这是首例关于尿道周围注射聚四氟乙烯后形成聚四氟乙烯囊肿的报告。本报告介绍了该患者的病史、影像学检查、细胞病理学检查以及文献复习情况。
