McKinney C D, Gaffey M J, Gillenwater J Y
Department of Anatomic Pathology, University of Virginia Health Sciences Center, Charlottesville.
J Urol. 1995 Jan;153(1):149-51. doi: 10.1097/00005392-199501000-00053.
Periurethral polytetrafluoroethylene (Teflon) injections have been reported to be successful for the treatment of urinary incontinence after transurethral resection or radical prostatectomy. However, the use of polytetrafluoroethylene is controversial due to reports of distant migration and granulomatous reaction after periurethral injection. We report on a patient with a history of periurethral polytetrafluoroethylene injection for postoperative stress incontinence in whom bladder outlet obstruction developed and who underwent repeat transurethral resection 9 years later. Pathological examination revealed that the material responsible for the obstruction was almost totally composed of a foreign body giant cell response to the polytetrafluoroethylene implant ("teflonoma").
据报道，尿道周围注射聚四氟乙烯（特氟龙）对于经尿道前列腺切除术或根治性前列腺切除术后尿失禁的治疗是成功的。然而，由于有尿道周围注射后远处迁移和肉芽肿反应的报道，聚四氟乙烯的使用存在争议。我们报告了一名有尿道周围注射聚四氟乙烯治疗术后压力性尿失禁病史的患者，该患者出现了膀胱出口梗阻，并在9年后接受了再次经尿道切除术。病理检查显示，造成梗阻的物质几乎完全由对聚四氟乙烯植入物的异物巨细胞反应（“特氟龙瘤”）组成。
