肌肉活检的效用。

The utility of muscle biopsy.

作者信息

Lacomis David

机构信息

University of Pittsburgh Medical Center, UPMC Presbyterian, 200 Lothrop Street, F878, Pittsburgh, PA 15213, USA.

出版信息

Curr Neurol Neurosci Rep. 2004 Jan;4(1):81-6. doi: 10.1007/s11910-004-0017-5.

DOI:10.1007/s11910-004-0017-5

PMID:14683634

Abstract

Despite major advances in molecular genetics, histopathologic evaluation of muscle biopsy specimens continues to provide important diagnostic information in patients with suspected muscle diseases and in patients with vasculitic neuropathies. Muscle biopsy specimens are used in diagnosing many inherited as well as inflammatory and toxic myopathies. Furthermore, the study of muscle histopathology can also enhance our understanding of disease pathogenesis.

摘要

尽管分子遗传学取得了重大进展，但对肌肉活检标本进行组织病理学评估，对于疑似肌肉疾病患者和血管炎性神经病患者而言，仍能提供重要的诊断信息。肌肉活检标本可用于诊断多种遗传性、炎性及中毒性肌病。此外，对肌肉组织病理学的研究还能增进我们对疾病发病机制的理解。