Essential muscle pathology for the rheumatologist.

This review introduces/refreshes some basic histopathologic methods and findings of skeletal muscle biopsies with emphasis on those diseases commonly encountered in a rheumatologist's practice. The 3 general areas of myopathology discussed are metabolic myopathies, toxic myopathies, and inflammatory myopathies. The authors, neuropathologists, hope to provide in this article what they think are some commonalities and disease-specific methods in their pathologic workup as well as a practical approach to the collaboration that pathologists undertake with their rheumatology colleagues to come to a working diagnosis.