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[上气道梗阻的临床管理:会厌炎和喉气管支气管炎]

[Clinical management of upper airway obstruction: epiglottitis and laryngotracheobronchitis].

作者信息

Amantéa S L, Silva A P

机构信息

Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.

出版信息

J Pediatr (Rio J). 1999 Nov;75 Suppl 2:S177-84. doi: 10.2223/jped.387.

Abstract

OBJECTIVE

To present current concepts on diagnosis and treatment of upper airway obstruction, mainly related to differential diagnosis between acute viral laryngotracheobronchitis and epiglottitis.METHODS: Bibliographic review covering the last ten years, using both Medline system and direct research. The most relevant articles published about the subject were selected.RESULTS: Viral laryngotracheobronchitis is an acute self-limited disease of the upper airway in a child, clinically characterized by barking cough, stridor, hoarse voice, and upper respiratory symptoms. The disease is diagnosed by clinical signs and symptoms. Rarely, if no immediate airway management is needed, radiography of the neck may help to exclude other entities that cause laryngeal obstruction. In contrast to viral laryngotracheobronchitis, epiglottitis is characterized by inflammation of the supraglottic tissues and is caused mainly by Haemophilus influenzae type b. A previously healthy child suddenly develops a sore throat and fever. Within hours after the onset of symptoms the patient looks toxic, swallowing is painful and breathing is difficult. Drooling and cervical hyperextension are frequently present. Lateral neck radiograph is rarely required to the diagnosis and may delay appropriate management of the airway. Moderate viral laryngotracheobronchitis with stridor at rest and retractions should be treated with steroids (systemic or nebulized) and nebulized epinephrine. Severe viral laryngotracheobronchitis should be treated aggressively while arregements are made for endotracheal intubation. The diagnosis of epiglottitis requires immediate endotracheal intubation in the appropriate unit (emergency department, intensive care unit or surgical unit) and antimicrobial therapy. Alternatively at some medical centers children with severe upper airway obstruction have been treated with a mixture of helium and oxygen (70 to 80% concentration of helium) instead of room air or pure oxygen to avoid intubation.CONCLUSIONS: There are different levels of care for patients with upper airway obstruction, depending on their clinical presentation. The clinical manifestations of viral laryngotracheobronchitis may be confused with the presentation of epiglottitis. Despite this observation we believe that differential diagnosis between viral laryngotracheobronchitis and epiglottitis rests on clinical grounds.

摘要

目的

阐述上气道梗阻的诊断与治疗的当前概念,主要涉及急性病毒性喉气管支气管炎与会厌炎的鉴别诊断。方法:使用Medline系统及直接检索进行过去十年的文献综述。选取了关于该主题发表的最相关文章。结果:病毒性喉气管支气管炎是儿童上气道的一种急性自限性疾病,临床特征为犬吠样咳嗽、喘鸣、声音嘶哑及上呼吸道症状。该病通过临床体征和症状进行诊断。极少情况下,如果不需要立即进行气道管理,颈部X线检查可能有助于排除其他导致喉梗阻的疾病。与会厌炎不同,病毒性喉气管支气管炎的特征是声门上组织炎症,主要由b型流感嗜血杆菌引起。先前健康的儿童突然出现咽痛和发热。症状出现数小时内,患者表现出中毒症状,吞咽疼痛且呼吸困难。常伴有流涎和颈部过伸。诊断时很少需要颈部侧位X线片,且可能会延误气道的适当处理。中度病毒性喉气管支气管炎伴静息时喘鸣及吸气三凹征,应使用类固醇(全身或雾化)及雾化肾上腺素治疗。重度病毒性喉气管支气管炎应在安排气管插管的同时积极治疗。会厌炎的诊断需要在合适的科室(急诊科、重症监护室或外科病房)立即进行气管插管及抗菌治疗。在一些医疗中心,替代的方法是,对于严重上气道梗阻的儿童,使用氦氧混合气体(氦浓度为70%至80%)而非室内空气或纯氧进行治疗,以避免插管。结论:根据临床表现,上气道梗阻患者有不同的护理级别。病毒性喉气管支气管炎的临床表现可能与会厌炎的表现相混淆。尽管如此,我们认为病毒性喉气管支气管炎与会厌炎的鉴别诊断基于临床依据。

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