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海洛因使用者中的自杀未遂情况:澳大利亚治疗结果研究(ATOS)的12个月随访结果

Attempted suicide among heroin users: 12-month outcomes from the Australian Treatment Outcome Study (ATOS).

作者信息

Darke Shane, Williamson Anna, Ross Joanne, Teesson Maree

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia.

出版信息

Drug Alcohol Depend. 2005 May 9;78(2):177-86. doi: 10.1016/j.drugalcdep.2004.10.009. Epub 2004 Dec 9.

Abstract

A cohort of 495 heroin users, recruited for the Australian Treatment Outcome Study (ATOS), were re-interviewed at 12 months regarding suicide attempts over the follow-up period. The proportion who had attempted suicide in the 12 months since baseline was not significantly different from that reported in the 12 months preceding ATOS enrolment (12.2% versus 9.1%), and attempted suicide did not decline significantly in any of the index treatment groups. Among males, there was no significant reduction in attempted suicide (8.7% versus 8.1%). Among females, however, the proportion reporting an attempt declined significantly from 19.7 to 9.8%. Of those who reported suicidal ideation at baseline, 22.8% made an attempt over the follow-up period, as did 19.0% of those who had major depression. Large, and significant, declines in suicidal ideation (23.1% versus 6.9%) and major depression (25.5% versus 10.9%) occurred over the study period. Independent predictors of a suicide attempt over the follow-up period were: social isolation, having made an attempt in the preceding 12 months, suicidal ideation at baseline, a greater number of treatment episodes and higher levels of baseline polydrug use.

摘要

一项针对495名海洛因使用者的队列研究,这些人参与了澳大利亚治疗结果研究(ATOS),在随访期12个月时再次接受访谈,询问其自杀未遂情况。自基线起12个月内自杀未遂的比例与ATOS入组前12个月报告的比例无显著差异(分别为12.2%和9.1%),且在任何一个主要治疗组中自杀未遂情况均未显著下降。在男性中,自杀未遂情况无显著减少(分别为8.7%和8.1%)。然而,在女性中,报告有自杀未遂的比例从19.7%显著下降至9.8%。在基线时有自杀意念的人中,22.8%在随访期内有过自杀未遂行为,患有重度抑郁症的人中这一比例为19.0%。在研究期间,自杀意念(从23.1%降至6.9%)和重度抑郁症(从25.5%降至10.9%)均出现了大幅且显著的下降。随访期内自杀未遂的独立预测因素包括:社会隔离、在前12个月内有过自杀未遂行为、基线时有自杀意念、更多的治疗疗程以及更高的基线多药使用水平。

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