Darke Shane, Williamson Anna, Ross Joanne, Teesson Maree
National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia.
Drug Alcohol Depend. 2005 May 9;78(2):177-86. doi: 10.1016/j.drugalcdep.2004.10.009. Epub 2004 Dec 9.
A cohort of 495 heroin users, recruited for the Australian Treatment Outcome Study (ATOS), were re-interviewed at 12 months regarding suicide attempts over the follow-up period. The proportion who had attempted suicide in the 12 months since baseline was not significantly different from that reported in the 12 months preceding ATOS enrolment (12.2% versus 9.1%), and attempted suicide did not decline significantly in any of the index treatment groups. Among males, there was no significant reduction in attempted suicide (8.7% versus 8.1%). Among females, however, the proportion reporting an attempt declined significantly from 19.7 to 9.8%. Of those who reported suicidal ideation at baseline, 22.8% made an attempt over the follow-up period, as did 19.0% of those who had major depression. Large, and significant, declines in suicidal ideation (23.1% versus 6.9%) and major depression (25.5% versus 10.9%) occurred over the study period. Independent predictors of a suicide attempt over the follow-up period were: social isolation, having made an attempt in the preceding 12 months, suicidal ideation at baseline, a greater number of treatment episodes and higher levels of baseline polydrug use.
一项针对495名海洛因使用者的队列研究,这些人参与了澳大利亚治疗结果研究(ATOS),在随访期12个月时再次接受访谈,询问其自杀未遂情况。自基线起12个月内自杀未遂的比例与ATOS入组前12个月报告的比例无显著差异(分别为12.2%和9.1%),且在任何一个主要治疗组中自杀未遂情况均未显著下降。在男性中,自杀未遂情况无显著减少(分别为8.7%和8.1%)。然而,在女性中,报告有自杀未遂的比例从19.7%显著下降至9.8%。在基线时有自杀意念的人中,22.8%在随访期内有过自杀未遂行为,患有重度抑郁症的人中这一比例为19.0%。在研究期间,自杀意念(从23.1%降至6.9%)和重度抑郁症(从25.5%降至10.9%)均出现了大幅且显著的下降。随访期内自杀未遂的独立预测因素包括:社会隔离、在前12个月内有过自杀未遂行为、基线时有自杀意念、更多的治疗疗程以及更高的基线多药使用水平。