Werlin S L, Esterly N B, Oechler H
Department of Pediatrics, Medical College of Wisconsin, Milwaukee 53226.
J Am Acad Dermatol. 1992 Nov;27(5 Pt 2):893-5. doi: 10.1016/0190-9622(92)70276-l.
We describe a child who had unilateral hypertrophy of the vulva, a rare extraintestinal manifestation of Crohn's disease. A biopsy specimen revealed a noncaseating granuloma. Flexible sigmoidoscopic examination revealed punctate 1 mm lesions with surrounding erythema in the rectum and sigmoid colon. Response to treatment with sulfasalazine was excellent. Gastrointestinal symptoms developed 1 year later when sulfasalazine was discontinued.
我们描述了一名患有单侧外阴肥大的儿童,这是克罗恩病一种罕见的肠外表现。活检标本显示为非干酪样肉芽肿。乙状结肠镜检查发现直肠和乙状结肠有1毫米的点状病变及周围红斑。对柳氮磺胺吡啶治疗反应良好。1年后停用柳氮磺胺吡啶时出现胃肠道症状。