Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Institute of Women's Life Science, Yonsei University College of Medicine, Seoul, Korea.
BMC Womens Health. 2021 Aug 28;21(1):316. doi: 10.1186/s12905-021-01449-4.
This case report presents a case of Vulvar Crohn's disease (VCD) in an adolescent, that is an uncommon manifestation of Crohn's disease (CD) without gastrointestinal symptoms. Before treating CD itself with proper medication, vulvar abscess continued to recur without improvement.
We report the case of an 18-year-old woman with VCD. After treatment with azathioprine 50 mg daily and mesalazine 1 g three times daily, vulvar lesions resolved after 6 weeks. We collected electronic medical data on patient characteristics, and evaluated findings of physical examinations, pelvic MRI, and biopsy specimen obtained from gastroduodenoscopy/colonoscopy.
VCD is a rare manifestation of CD that may be misdiagnosed in the absence of gastrointestinal symptoms leading to delayed treatment. If a patient has an unexplained vulvar inflammatory lesion and with repeated failed surgical treatment, gynecologists should consider the possibility of a VCD.
本病例报告介绍了一例青少年外阴克罗恩病（VCD），这是一种无胃肠道症状的克罗恩病（CD）的罕见表现。在使用适当药物治疗 CD 本身之前，外阴脓肿持续复发，没有改善。
我们报告了一例 18 岁女性 VCD 病例。在每天使用 50mg 硫唑嘌呤和每天三次 1g 美沙拉嗪治疗后，外阴病变在 6 周后消退。我们收集了患者特征的电子医疗数据，并评估了体格检查、盆腔 MRI 和经胃肠镜/结肠镜获取的活检标本的结果。
VCD 是 CD 的一种罕见表现，如果没有胃肠道症状，可能会导致误诊，从而导致治疗延误。如果患者有不明原因的外阴炎症性病变且反复手术治疗失败，妇科医生应考虑 VCD 的可能性。
