Saray Aydin
Kirikkale University Medical School, Kirikkale, Turkey.
Aesthetic Plast Surg. 2003 Sep-Oct;27(5):368-75. doi: 10.1007/s00266-003-3012-3. Epub 2003 Dec 29.
Soft tissue loss or damage can occur for various reasons, including trauma, surgery, and disease. Reconstruction of normal contours can be achieved by using either alloplastic implants or autogenous tissues. Permacol, a dermal replacement material derived from fibrous acellular porcine dermal collagen, has been used for restoration of soft-tissue contours in the face. Eight patients were treated with porcine collagen in an attempt to achieve a smooth contour and a natural feel. Clinically visible soft tissue defects were successfully covered and aesthetic results were satisfying. Transient swelling that subsided within a week was noted in all patients. Meticulous and aseptic technique is mandatory for Permacol use. With this limited experience, Permacol was successfully used as a filler implant in reconstruction of post-traumatic soft-tissue defects, correcting post-parotidectomy hallowing and secondary nasal surgery to cover osseocartilaginous irregularities. However, there is a potential risk of inflammation and skin contractures in thin-skinned patients when implants are placed superficially.
软组织缺失或损伤可能由多种原因引起，包括创伤、手术和疾病。通过使用异体植入物或自体组织可以实现正常轮廓的重建。Permacol是一种源自无细胞猪真皮胶原蛋白的真皮替代材料，已被用于面部软组织轮廓的恢复。八名患者接受了猪胶原蛋白治疗，试图实现平滑的轮廓和自然的触感。临床上可见的软组织缺损得到成功覆盖，美学效果令人满意。所有患者均出现了在一周内消退的短暂肿胀。使用Permacol时必须采用细致的无菌技术。基于这一有限的经验，Permacol成功地用作填充植入物，用于创伤后软组织缺损的重建、纠正腮腺切除术后的凹陷以及二次鼻整形手术以覆盖骨软骨不规则处。然而，在薄皮肤患者中，当植入物放置在浅表时，存在炎症和皮肤挛缩的潜在风险。
