Alwitry A, Burns S J, Abercrombie L C
Eye, Ear, Nose and Throat Centre, Queens Medical Centre, Nottingham, United Kingdom.
Orbit. 2006 Sep;25(3):253-6. doi: 10.1080/01676830600575568.
To present a small case series of orbital implant exposures treated with porcine dermal collagen (Permacol, Tissue Science Laboratories PLC, Aldershot, Hants, UK) patching.
A retrospective chart review of three cases of orbital implant exposure treated with Permacol patching.
Three cases were identified. There were 4 operative episodes of Permacol patching (one socket had two attempts at permacol patching). In all 4 cases the patch rapidly failed and melted away leaving behind the orbital implant exposure. All 3 patients required implant removal.
Orbital implant exposure remains a major long-term complication of evisceration and enucleation procedures. On the basis of our experience, we would not recommend using Permacol as a non-autologous material for covering exposed Medpor (Medpor, Porex Surgical, Atlanta, Georgia, USA) orbital implants. Further study is required to fully assess the safety and efficacy profile of Permacol in socket surgery.
介绍一组采用猪真皮胶原蛋白（Permacol，组织科学实验室有限公司，英国汉普郡奥尔德肖特）修补治疗眼眶植入物暴露的小病例系列。
对3例采用Permacol修补治疗眼眶植入物暴露的病例进行回顾性病历审查。
共确定3例。进行了4次Permacol修补手术（1例眼窝进行了2次Permacol修补尝试）。在所有4例中，补片迅速失效并融化，眼眶植入物暴露。所有3例患者均需取出植入物。
眼眶植入物暴露仍然是眼球摘除术和眼球摘除术后的主要长期并发症。根据我们的经验，我们不建议使用Permacol作为非自体材料覆盖暴露的Medpor（美国佐治亚州亚特兰大Porex外科公司的Medpor）眼眶植入物。需要进一步研究以全面评估Permacol在眼窝手术中的安全性和有效性。
