Katayama Ichiro, Hirayama Minako, Eishi Kumiko
Department of Dermatology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, 852-8501 Japan.
Eur J Dermatol. 2003 Sep-Oct;13(5):505-8.
We report a sporadic case of eruptive milia with histopathological features of basaloid follicular hamartoma which developed in an 8 year-old Japanese girl. Multiple milia and comedo-like eruptions were present at birth and gradually increased in number and spread over the extremities. Histopathologically, keratotic cysts with trichilemmal keratinization and features of basaloid follicular hamartoma were observed without any histological findings of basal cell epithelioma or trichoepithelioma. Reduced sweating was observed after iontophoretically applied acetylcholine on the forearm. Nevus of Ota and thyroid goiter were complications.
我们报告了一例散发的发疹性粟丘疹病例,该病例发生在一名8岁的日本女孩身上,具有基底细胞样毛囊错构瘤的组织病理学特征。出生时即出现多发性粟丘疹和粉刺样皮疹,数量逐渐增加并蔓延至四肢。组织病理学检查发现角化囊肿伴毛透明角化,以及基底细胞样毛囊错构瘤的特征,未发现基底细胞上皮瘤或毛发上皮瘤的任何组织学表现。在前臂经离子电渗法应用乙酰胆碱后,观察到出汗减少。太田痣和甲状腺肿大为并发症。