Suppr超能文献

儿童肾上腺素自我给药:当前处方实践调查及改进建议

Self-administration of epinephrine in children: a survey of current prescription practice and recommendations for improvement.

作者信息

Hughes J L, Stewart M

机构信息

Department of Child Health, Institute of Clinical Science, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BJ.

出版信息

Ulster Med J. 2003 Nov;72(2):80-5.

Abstract

The prevalence of peanut allergy is increasing rapidly and many children are now prescribed self-injectable epinephrine as part of their management. We aimed to examine the current extent of self-injectable epinephrine dispensing to children in the Eastern Health and Social Services Board (EHSSB), Northern Ireland, including indications for prescription, investigations performed, information and training provided and actual usage. Dispensing records held by the EHSSB were examined for the period May to August 1998. All general practitioners prescribing 'Epipens' during this period were contacted and asked to identify the patient and provide contact details. Information was gathered using postal questionnaires sent to General Practitioners and parents. A total of 104 'Epipen' prescriptions were dispensed. Thirty-seven (36%) general practitioners responded to the initial questionnaire; of these 36 (35%) were suitable for analysis. Thirty-four parents were then contacted; 28 (82%) returned questionnaires were reviewed. The commonest indication for 'Epipen' prescription was peanut allergy (32 of 36 (89%) general practitioner responses; 25 of 28 (89%) parent responses). Twenty-six (72%) children had been seen by a specialist; all except one had either blood or skin tests. Six of the remaining eight children had no investigations. General practitioners reported 14 (39%) parents to have basic life support training, compared with six (21%) parents. Eighteen (64%) parents had been given written information regarding their child's allergy, nine (32%) had been referred to a dietician and seven (25%) children wore a medical warning bracelet. The Epipen had been used by three children; all three had multiple food allergies. This study has identified a great variability in the management of children with allergy including the need for specialist referral, further investigation, written allergy advice, referral to a dietician and formalised training in basic life support and administration of epinephrine. It suggests a lack of consensus amongst health care professionals as to the best practice in the management of potentially life threatening food allergy and indicates, at least, a need for better multidisciplinary communication.

摘要

花生过敏的患病率正在迅速上升,现在许多儿童在治疗过程中被开了自动注射肾上腺素笔作为治疗的一部分。我们旨在调查北爱尔兰东部卫生和社会服务委员会(EHSSB)向儿童发放自动注射肾上腺素笔的当前情况,包括处方适应症、进行的检查、提供的信息和培训以及实际使用情况。对EHSSB在1998年5月至8月期间保存的发放记录进行了检查。在此期间所有开“肾上腺素笔”处方的全科医生都被联系,并被要求确认患者身份并提供联系方式。通过向全科医生和家长发送邮政问卷来收集信息。总共发放了104份“肾上腺素笔”处方。37名(36%)全科医生回复了初始问卷;其中36名(35%)适合进行分析。随后联系了34名家长;对28份(82%)返回的问卷进行了审查。“肾上腺素笔”处方最常见的适应症是花生过敏(36名全科医生回复中有32名(89%);28名家长回复中有25名(89%))。26名(72%)儿童看过专科医生;除一名儿童外,其他儿童都进行了血液或皮肤测试。其余八名儿童中有六名未进行任何检查。全科医生报告称14名(39%)家长接受过基本生命支持培训,而家长报告的这一比例为6名(21%)。18名(64%)家长收到了关于其孩子过敏情况的书面信息,9名(32%)家长被转介给营养师,7名(25%)儿童佩戴了医疗警示手环。有三名儿童使用过肾上腺素笔;这三名儿童都对多种食物过敏。这项研究发现,在过敏儿童的治疗方面存在很大差异,包括需要专科转诊、进一步检查、书面过敏建议、转介给营养师以及在基本生命支持和肾上腺素给药方面进行正规培训。这表明医疗保健专业人员对于潜在危及生命的食物过敏的最佳治疗方法缺乏共识,至少表明需要更好的多学科沟通。

相似文献

2
Prescription of adrenaline auto-injectors for potential anaphylaxis--a population survey.
Public Health. 2003 Jul;117(4):256-9. doi: 10.1016/S0033-3506(03)00034-9.
3
Parental knowledge and use of epinephrine auto-injector for children with food allergy.
Pediatr Allergy Immunol. 2006 May;17(3):221-6. doi: 10.1111/j.1399-3038.2006.00391.x.
4
Parental use of EpiPen for children with food allergies.
J Allergy Clin Immunol. 2005 Jul;116(1):164-8. doi: 10.1016/j.jaci.2005.03.039.
5
Factors determining the ability of parents to effectively administer intramuscular adrenaline to food allergic children.
Pediatr Allergy Immunol. 2006 May;17(3):227-9. doi: 10.1111/j.1399-3038.2006.00392.x.
6
Use of multiple doses of epinephrine in food-induced anaphylaxis in children.
J Allergy Clin Immunol. 2008 Jul;122(1):133-8. doi: 10.1016/j.jaci.2008.04.031. Epub 2008 Jun 10.

本文引用的文献

2
Utility of food-specific IgE concentrations in predicting symptomatic food allergy.
J Allergy Clin Immunol. 2001 May;107(5):891-6. doi: 10.1067/mai.2001.114708.
3
Lessons for management of anaphylaxis from a study of fatal reactions.
Clin Exp Allergy. 2000 Aug;30(8):1144-50. doi: 10.1046/j.1365-2222.2000.00864.x.
4
Quantitative IgE antibody assays in allergic diseases.
J Allergy Clin Immunol. 2000 Jun;105(6 Pt 1):1077-84. doi: 10.1067/mai.2000.107041.
5
Use assessment of self-administered epinephrine among food-allergic children and pediatricians.
Pediatrics. 2000 Feb;105(2):359-62. doi: 10.1542/peds.105.2.359.
6
Resolution of peanut allergy: case-control study.
BMJ. 1998 Apr 25;316(7140):1271-5. doi: 10.1136/bmj.316.7140.1271.
7
Epinephrine absorption in children with a history of anaphylaxis.
J Allergy Clin Immunol. 1998 Jan;101(1 Pt 1):33-7. doi: 10.1016/S0091-6749(98)70190-3.
8
Peanut allergy--current status and future challenges.
Clin Exp Allergy. 1997 Nov;27(11):1240-6.
10
Anaphylaxis in children: a 5-year experience.
Pediatrics. 1997 Jan;99(1):E7. doi: 10.1542/peds.99.1.e7.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验