Thomas Leno, Kwok Young, Edelman Martin J
Division of Hematology-Oncology, Greenebaum Cancer Center, University of Maryland Medical Center, 22 South Greene Street, Baltimore, MD 21201, USA.
Curr Treat Options Oncol. 2004 Feb;5(1):51-62. doi: 10.1007/s11864-004-0006-6.
Paraneoplastic syndromes are common complications of lung cancer. Although most frequently associated with advanced disease, paraneoplastic syndromes may also occur at early stages. Occasionally, the paraneoplastic syndrome may be the presenting symptom of lung cancer. For most paraneoplastic syndromes, the best treatment is to treat the underlying malignancy. However, in many cases, treatment of moderate efficacy or urgent therapy is required. Specific recommendations for the management of the most common paraneoplastic syndromes, including cachexia, hypercalcemia, and hyponatremia, are provided.
副肿瘤综合征是肺癌常见的并发症。虽然大多与晚期疾病相关，但副肿瘤综合征也可能在疾病早期出现。偶尔，副肿瘤综合征可能是肺癌的首发症状。对于大多数副肿瘤综合征，最佳治疗方法是治疗潜在的恶性肿瘤。然而，在许多情况下，需要采用疗效中等的治疗方法或进行紧急治疗。本文提供了针对最常见副肿瘤综合征（包括恶病质、高钙血症和低钠血症）管理的具体建议。
