阿托伐他汀80毫克对血清低密度脂蛋白胆固醇水平<130毫克/分升的患者内皮细胞功能（前臂血流量）的影响。
Effect of atorvastatin 80 mg on endothelial cell function (forearm blood flow) in patients with pretreatment serum low-density lipoprotein cholesterol levels <130 mg/dl.
作者信息
Wassmann Sven, Ribaudo Nicole, Faul Anna, Laufs Ulrich, Böhm Michael, Nickenig Georg
机构信息
Medizinische Klinik und Poliklinik, Innere Medizin III, Universitätskliniken des Saarlandes, Homburg/Saar, Germany.
出版信息
Am J Cardiol. 2004 Jan 1;93(1):84-8. doi: 10.1016/j.amjcard.2003.09.018.
The effect of 6-week treatment with 80 mg/day atorvastatin on vascular function in the forearm was investigated in 18 patients with mean pretreatment serum low-density lipoprotein cholesterol concentrations of 112 +/- 4 mg/dl in a double-blind, placebo-controlled, randomized study. Statin treatment improved hyperemic forearm blood flow and decreased serum markers of oxidative stress and inflammation.
在一项双盲、安慰剂对照、随机研究中，对18例治疗前血清低密度脂蛋白胆固醇平均浓度为112±4mg/dl的患者，研究了每天80mg阿托伐他汀进行6周治疗对前臂血管功能的影响。他汀类药物治疗改善了前臂充血性血流，并降低了氧化应激和炎症的血清标志物。
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