Spiridonov A A, Ambat'ello S G, Samuilova D Sh, Khurges I S, Ivanova L S, Dmitrieva V A
Khirurgiia (Mosk). 1992 May-Jun(5-6):23-9.
The authors examined 29 patients with aorto-arteritis of unspecific origin of different duration and variants of affections of the major vessels. The patients were divided into groups with active and inactive course of the inflammatory process. The changes of immunological values and the phagocytosis data were more marked in the group with the active phase of the disease. These changes correlated with the data on unspecific inflammation and the clinical picture. Twenty-two patients were treated by hemosorption and immunocorrective measures. The fibrinogen concentration reduced, the ESR was normalized, and C-reactive protein became negative. The concentration of circulating immune complex and immunoglobulins diminished, the phagocytosis values became close to normal. It is concluded that hemosorption is an effective method of correction of immunological disorders in unspecific aorto-arteritis, both as an independent therapeutic method and as a measure of preoperative management.
作者研究了29例不同病程及主要血管受累不同类型的非特异性主动脉炎患者。将患者分为炎症过程呈活动期和非活动期的两组。疾病活动期组的免疫学指标变化及吞噬作用数据更为明显。这些变化与非特异性炎症数据及临床表现相关。22例患者接受了血液吸附及免疫纠正措施治疗。纤维蛋白原浓度降低，血沉恢复正常，C反应蛋白转阴。循环免疫复合物及免疫球蛋白浓度降低，吞噬作用值接近正常。结论是，血液吸附作为一种独立的治疗方法以及术前处理措施，是纠正非特异性主动脉炎免疫紊乱的有效方法。
