Duffy Rosemary E, Couto Braulio, Pessoa Jussara M, Starling Carlos, Pinheiro Silma, Pearson Michele L, Arduino Matthew J, Mattson Barbara J, Jarvis William R
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Infect Control Hosp Epidemiol. 2003 Dec;24(12):955-60. doi: 10.1086/502166.
To report the results of our preintervention investigation and subsequent 19-month three-phase intervention study designed to reduce pyrogenic reactions among patients undergoing cardiac catheterization using reprocessed catheters.
A case-control study for the preintervention period and a prospective cohort study for the intervention period.
A 400-bed hospital in Belo Horizonte, Brazil.
Any patient undergoing cardiac catheterization in the hospital.
Three intervention phases were implemented to improve the quality of the water supplied to the cardiac catheter reprocessing laboratory. Standard operating procedures for reprocessing cardiac catheters were established and reprocessing staff were trained and educated.
The rate of pyrogenic reactions decreased significantly during the intervention phases, from 12.8% (159 of 1,239) in phase 1 to 5.3% (38 of 712) in phase 2 to 0.5% (4 of 769) in phase 3 (chi-square test for linear trend, 97.5; P < .001).
Improving water quality and using standard operating procedures for reprocessing catheters can prevent pyrogenic reactions in hospitalized patients.
报告我们的干预前调查结果以及随后为期19个月的三阶段干预研究结果,该研究旨在减少使用经再处理导管进行心脏导管插入术的患者中的热原反应。
干预前期为病例对照研究,干预期为前瞻性队列研究。
巴西贝洛奥里藏特一家拥有400张床位的医院。
在该医院接受心脏导管插入术的任何患者。
实施了三个干预阶段,以提高供应给心脏导管再处理实验室的水的质量。制定了心脏导管再处理的标准操作程序,并对再处理人员进行了培训和教育。
在干预阶段,热原反应发生率显著下降,从第1阶段的12.8%(1239例中的159例)降至第2阶段的5.3%(712例中的38例),再降至第3阶段的0.5%(769例中的4例)(线性趋势卡方检验,97.5;P <.001)。
改善水质并使用导管再处理的标准操作程序可预防住院患者发生热原反应。