Hagiwara M, Sakai M, Nagaoka S, Nakano S, Okano T, Okada T, Katayama K
First Department of Surgery, School of Medicine, St. Marianna University, Kawasaki, Japan.
Nihon Geka Gakkai Zasshi. 1992 Sep;93(9):1153-5.
We investigated the effects of EIS and esophageal transection on treatment of esophageal varices and the late result of EIS treatment group with that of surgical treatment group. One hundred and forty-seven patients underwent esophageal transection and 244 patients injection sclerotherapy in our institute. 1. The 5-year cumulative survival rate in patients with EIS was 58%, while 62% in those with transection. 2. Judging from the findings of varices after treatment which showed the negative red color sign, or changes from F2 or F3 to F1, the effect of two methods were 72% in operation group and 73% in EIS group, respectively. 3. There was no significant difference in the rates of rebleeding between EIS (7.8%) and operation (10.2%) groups. 4. Prognosis of esophageal varices treated with EIS or operation was considered to depend on the Child's classification. We conclude that endoscopic sclerotherapy should be considered to be the first choice of treatment for esophageal varices.
我们研究了内镜硬化剂注射术（EIS）和食管横断术对食管静脉曲张治疗的效果，以及EIS治疗组与手术治疗组的远期结果。我院147例患者接受了食管横断术，244例患者接受了内镜硬化剂注射治疗。1. EIS治疗患者的5年累积生存率为58%，而接受食管横断术患者的5年累积生存率为62%。2. 从治疗后静脉曲张的表现来看，即红色征阴性，或从F2或F3级变为F1级，两种方法的有效率在手术组为72%，在EIS组为73%。3. EIS组（7.8%）和手术组（10.2%）的再出血率无显著差异。4. 采用EIS或手术治疗食管静脉曲张的预后被认为取决于Child分级。我们得出结论，内镜硬化剂注射治疗应被视为食管静脉曲张治疗的首选方法。
