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洗衣粉酶对工人和使用者的临床及免疫学影响（作者译）

[Clinical and immunological effect of washing powder enzymes on workers and users (author's transl)].

作者信息

Cernelc D, Jurc F, Cernelc P, Gabrovsek P, Gabrovsek L

出版信息

Allerg Immunol (Leipz). 1977;23(3):185-92.

PMID:147016
Abstract

For 141 workers in the washing powder industry in Maribor (Group A) and 68 workers of vegetables' shops to determine the risk of sensitization for house-wives handling enzymes detergents (Group B) as a control group the results of diagnostic investigations as well as analyses of protective measures to proteolytic enzymes are contrasted. Within the Group A eight subgroups according to exposition to proteolytic enzymes powder are evaluated. Especially elucited are the results of skin testing (Scratch-tets with Maxatase, Alcalase and culture extract from B. subtilis) and with proteolytic enzymes powder, the lung function tests (vitalogram, spirogram, pneumometer-test diffusion-test and sometimes the blood gas tests), cytological examinations of nasal mucosa and simultaneously taking a blood sample for determination of concentration of total serum IgE and precipitins to enzymes extracts.

摘要

对马里博尔洗衣粉行业的141名工人（A组）以及68名蔬菜店工人进行研究，后者作为对照组，以确定处理含酶洗涤剂的家庭主妇的致敏风险（B组）。对比了诊断调查结果以及针对蛋白水解酶的防护措施分析。在A组中，根据对蛋白水解酶粉末的接触情况评估了八个亚组。特别阐述了皮肤测试（用Maxatase、Alcalase和枯草芽孢杆菌培养提取物进行划痕试验）以及蛋白水解酶粉末测试的结果、肺功能测试（肺活量图、肺量计图、肺量计测试、扩散测试，有时还包括血气测试）、鼻黏膜细胞学检查，同时采集血样以测定总血清IgE浓度和对酶提取物的沉淀素。

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