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[压力对分子内蛋白质动力学的作用机制]

[The mechanism of action of pressure on intramolecular protein dynamics].

作者信息

Panchenko A R, Shaĭtan K V

出版信息

Mol Biol (Mosk). 1992 Sep-Oct;26(5):1116-21.

PMID:1470176
Abstract

The physical mechanisms of pressure influence on the protein dynamics and parameters of Mossbauer spectra were investigated. The pressure effects measured for human serum albumin using Rayleigh Scattering of Mossbauer Radiation techniques were described using the model of local diffusion. Parameters of this model were determined by analysing the experimental data. As a result an estimation of approximate values for activation volumes was performed. It was shown that the obtained values are well consistent with the previous experimental results.

摘要

研究了压力对蛋白质动力学和穆斯堡尔谱参数影响的物理机制。利用穆斯堡尔辐射的瑞利散射技术测量了人血清白蛋白的压力效应,并采用局部扩散模型进行了描述。通过分析实验数据确定了该模型的参数。结果对活化体积的近似值进行了估算。结果表明,所得值与先前的实验结果吻合良好。

相似文献

1
[The mechanism of action of pressure on intramolecular protein dynamics].[压力对分子内蛋白质动力学的作用机制]
Mol Biol (Mosk). 1992 Sep-Oct;26(5):1116-21.
2
[Study of the dynamics of human serum albumin by coherent Rayleigh dispersion of Mossbauer radiation].
Mol Biol (Mosk). 1992 Nov-Dec;26(6):1389-96.
3
[The effect of high pressure of protein dynamics from Rayleigh scattering of Mossbauer irradiation data].[基于穆斯堡尔辐照数据瑞利散射的蛋白质动力学高压效应]
Dokl Akad Nauk SSSR. 1991;321(4):842-5.
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[A study of the effect of solvent composition and viscosity on the molecular dynamics of human serum albumin using Rayleigh scattering of Mössbauer radiation].
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[Study of protein dynamics using Mössbauer spectroscopy].[利用穆斯堡尔谱学研究蛋白质动力学]
Biofizika. 1987 Sep-Oct;32(5):761-74.
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Biofizika. 1987 Mar-Apr;32(2):210-4.
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Human serum albumin unfolding: a small-angle X-ray scattering and light scattering study.人血清白蛋白的去折叠:小角X射线散射和光散射研究
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Binding constant measurement by hyper-Rayleigh scattering: bilirubin-human serum albumin binding as a case study.通过超瑞利散射测量结合常数:以胆红素与人血清白蛋白的结合为例进行研究
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引用本文的文献

1
Protein compressibility, dynamics, and pressure.蛋白质的压缩性、动力学与压力。
Biophys J. 2000 Jul;79(1):511-25. doi: 10.1016/S0006-3495(00)76313-2.