Ruggeri Mirella, Lasalvia Antonio, Tansella Michele, Bonetto Chiara, Abate Maria, Thornicroft Graham, Allevi Liliana, Ognibene Paola
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italy.
Br J Psychiatry. 2004 Jan;184:48-57. doi: 10.1192/bjp.184.1.48.
Care for people with schizophrenia should address a wide range of outcomes, including professional and consumer perspectives.
To measure changes in psychopathology, functioning, needs for care and quality of life; to develop predictive models for each outcome domain; and to assess the frequency of 'good'and'poor' outcomes, as defined in a series of different definitions that use combinations of the four domains measured.
Three-year follow-up of a 1-year-treated prevalence cohort of 107 patients with an ICD-10 diagnosis of schizophrenia attending the South Verona community-based mental health service.
Mean symptom severity and some types of needs for care worsen, but quality of life shows no change. Functioning shows a non-significant trend to deteriorate. Between 32% and 42% of the variance in the four key outcomes was explained by our model. Different definitions of 'good'and 'poor' outcome included 0-31% of patients, depending on the definition used.
The 3-year outcome for schizophrenia depends on the domain of outcome used, whether staff or patient ratings are used and the stringency of the definitions used for good and poor outcome.
对精神分裂症患者的护理应涵盖广泛的结果，包括专业人员和患者的观点。
测量精神病理学、功能、护理需求和生活质量的变化；为每个结果领域建立预测模型；并根据一系列使用所测量的四个领域组合的不同定义，评估“良好”和“不良”结果的发生频率。
对107名国际疾病分类第十版（ICD-10）诊断为精神分裂症且在南维罗纳社区精神卫生服务机构接受了为期1年治疗的现患队列进行为期三年的随访。
平均症状严重程度和某些类型的护理需求恶化，但生活质量无变化。功能有恶化的不显著趋势。我们的模型解释了四个关键结果中32%至42%的方差。“良好”和“不良”结果的不同定义包括0%至31%的患者，具体取决于所使用的定义。
精神分裂症的三年结果取决于所使用的结果领域、使用的是工作人员还是患者评分以及用于定义良好和不良结果的严格程度。
