Bartelink M L, Wollersheim H, van de Lisdonk E, Spruijt R, van Weel C
Department of Internal Medicine, University of Nijmegen, Netherlands.
Neth J Med. 1992 Oct;41(3-4):149-52.
Studies that present prevalence rates for Raynaud's phenomenon show great variation. Figures range from a few to more than 20%. In this study, 508 patients who attended their general practitioner filled in a questionnaire dealing with symptoms of Raynaud's phenomenon. When strict criteria (cold digits, numbness and at least a biphasic discolouration) were applied, prevalence was 0.5% in males and 2.9% in females. When a monophasic white discolouration was included, prevalence rates increased by 5.4% in males and by 7.5% in females. The respective percentages became 10.4% and 21.2% when subjects with cold digits and at least a monophasic white or blue discolouration were included. Complaints of cold digits were present in 22.7% of the males and in 35% of the females. We conclude that a great deal of the variation in prevalence of Raynaud's phenomenon can be explained by differences in its definition.
关于雷诺现象患病率的研究结果差异很大。数据范围从百分之几到超过20%。在本研究中，508名到全科医生处就诊的患者填写了一份关于雷诺现象症状的问卷。当采用严格标准（手指发冷、麻木以及至少双相变色）时，男性患病率为0.5%，女性为2.9%。若纳入单相白色变色情况，男性患病率增加5.4%，女性增加7.5%。当纳入手指发冷且至少有单相白色或蓝色变色的受试者时，相应百分比分别变为10.4%和21.2%。男性中有22.7%、女性中有35%存在手指发冷的主诉。我们得出结论，雷诺现象患病率的很大一部分差异可由其定义的不同来解释。
