Thumann A, Bustos-Obregon E
Andrologia. 1978 Jan-Feb;10(1):22-5.
The effect of a "testicular extract" on spermatogonial proliferation in adult rats is comparatively studied both "in vivo" and "in vitro". Both in irradiated rats injected with "testicular extract" as in testicular fragments from irradiated rats incubated in culture medium, addition of "testicular extract" elicits an inhibition in thymidine-H3 uptake by type A spermatogonia. This is not the case for non irradiated rats or incubation of testicular samples from non irradiated animals after addition of "testicular extract". The "in vitro" system for assay of the spermatogonial chalone is used to analyze the general characteristics of this mitotic inhibitor.
对成年大鼠，在“体内”和“体外”条件下比较研究了“睾丸提取物”对精原细胞增殖的影响。在注射了“睾丸提取物”的受辐照大鼠以及在培养基中培养的来自受辐照大鼠的睾丸片段中，添加“睾丸提取物”均会抑制A型精原细胞对3H-胸腺嘧啶核苷的摄取。而对于未受辐照的大鼠或添加“睾丸提取物”后培养的来自未受辐照动物的睾丸样本，情况并非如此。用于测定精原细胞抑素的“体外”系统被用于分析这种有丝分裂抑制剂的一般特性。
