Chen Enping, Golchin Saeed, Blomdahl Sven
Glaucoma Service, St Erik's Eye Hospital, Stockholm, Sweden.
J Glaucoma. 2004 Feb;13(1):62-5. doi: 10.1097/00061198-200402000-00012.
To compare two regimens of SLT, ie, SLT with 25 laser spots on 90 degrees of trabecular meshwork and SLT with 50 laser spots on 180 degrees of trabecular meshwork in patients with open-angle glaucoma.
In a prospective clinical study, the authors compared pressure-lowering effect of SLT in 2 groups of patients; 1 group (32 patients) received SLT with 25 laser spots on 90 degrees of trabecular meshwork, the other group (32 patients) SLT with 50 laser spots on 180 degrees of trabecular meshwork.
There was no difference in the pressure reduction between these two treatment regimens. Moreover, the pressure reduction was not influenced by previous ALT treatments. The pigmentation in the trabecular meshwork is related to a delayed effect on the pressure lowering after SLT.
SLT with 25 laser spots on 90 degrees of trabecular meshwork has a similar pressure-lowering effect to SLT with 50 laser spots on 180 degrees of trabecular meshwork. The new treatment regimen with less laser spots could increase the repeatability of SLT and reduce potential tissue damage in the trabecular meshwork.
比较两种选择性激光小梁成形术（SLT）治疗方案，即对开角型青光眼患者在90度小梁网处进行25个激光点的SLT和在180度小梁网处进行50个激光点的SLT。
在一项前瞻性临床研究中，作者比较了两组患者SLT的降压效果；一组（32例患者）在90度小梁网处接受25个激光点的SLT，另一组（32例患者）在180度小梁网处接受50个激光点的SLT。
这两种治疗方案在降压方面没有差异。此外，降压效果不受既往氩激光小梁成形术（ALT）治疗的影响。小梁网中的色素沉着与SLT后降压的延迟效应有关。
在90度小梁网处进行25个激光点的SLT与在180度小梁网处进行50个激光点的SLT具有相似的降压效果。激光点较少的新治疗方案可提高SLT的可重复性，并减少小梁网潜在的组织损伤。
