Liang Patrick, Tan-Ong Millicent, Hoffman Gary S
Cleveland Clinic Foundation, Department of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland, Ohio 44195, USA.
J Rheumatol. 2004 Jan;31(1):102-6.
To provide an analysis of outcomes of vascular interventions in 20 patients with Takayasu's arteritis (TA) who received care at the Cleveland Clinic Foundation between 1979 and 2001.
We performed a retrospective chart review. The primary outcome measure of our review was patency of vessels as assessed by repeat invasive angiography or magnetic resonance angiography. The secondary outcome measures included periprocedural complications, morbidity, and mortality. Interventions included bypass grafts, patch angioplasty, endarterectomy, percutaneous transluminal angioplasty (PTA), or stent placement.
Sixty-two revascularization procedures were performed in 20 patients. Followup evaluations were available for 52 procedures. Eleven of 31 bypass grafts restenosed or occluded between one day to 168 months after surgery. Three of 7 PTA and 5 of 7 stents restenosed or became occluded after 1-72 months and 2-45 months of followup, respectively. There were no deaths associated with revascularization procedures.
Despite providing short term benefit, endovascular revascularization procedures are associated with a high failure rate in patients with TA.
分析1979年至2001年间在克利夫兰诊所基金会接受治疗的20例大动脉炎（TA）患者的血管介入治疗结果。
我们进行了一项回顾性病历审查。我们审查的主要结局指标是通过重复有创血管造影或磁共振血管造影评估的血管通畅情况。次要结局指标包括围手术期并发症、发病率和死亡率。干预措施包括搭桥术、补片血管成形术、动脉内膜切除术、经皮腔内血管成形术（PTA）或支架置入术。
20例患者共进行了62次血运重建手术。52次手术有随访评估结果。31例搭桥术中，11例在术后1天至168个月之间出现再狭窄或闭塞。7例PTA中有3例，7例支架中有5例分别在随访1 - 72个月和2 - 45个月后出现再狭窄或闭塞。血运重建手术无相关死亡病例。
尽管血管腔内血运重建手术能带来短期益处，但TA患者接受该手术的失败率较高。
