de Bree Eelco, Zoetmulder Frans A N, Keus Ronald B, Peterse Hans L, van Coevorden Frits
Department of Surgical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Huis, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.
Am J Surg. 2004 Jan;187(1):33-8. doi: 10.1016/j.amjsurg.2002.11.002.
The incidence of plantar fibromatosis (PF) is unknown. Sometimes PF tends to recur repetitively after surgical treatment. In our institute we have used postoperative radiotherapy in an attempt to diminish the change on recurrence.
The Dutch Network and National Database for Pathology (PALGA) was consulted to establish the incidence of plantar fibromatosis (PF). Data from 9 patients (11 feet) with PF referred to our institute for recurrent disease were analyzed and the role of postoperative radiotherapy in prevention of recurrence was studied.
An average of 1.2 operations for PF was performed per 100,000 citizens yearly in the Netherlands. Twenty-six operations were performed and postoperative radiotherapy was used in 6 cases. Plantar fasciectomy was associated with the lowest recurrence rate. After microscopically incomplete excision or excision of early recurrence (< or =6 months) alone all tumors recurred, while recurrence was rarely observed after adjuvant radiotherapy. However, radiotherapy was associated with significantly impaired functional outcome in 3 cases.
Plantar fibromatosis is relatively rare. Plantar fasciectomy seems to be the operation of choice. Although effective in decreasing the recurrence rate, adjuvant radiotherapy should be used very selectively because of its serious side effects.
足底纤维瘤病(PF)的发病率尚不清楚。有时PF在手术治疗后容易反复复发。在我们研究所,我们采用术后放疗以试图降低复发几率。
查阅荷兰病理学网络和国家数据库(PALGA)以确定足底纤维瘤病(PF)的发病率。分析了9例(11只足)因复发性疾病转诊至我们研究所的PF患者的数据,并研究了术后放疗在预防复发中的作用。
在荷兰,每年每10万公民平均进行1.2次PF手术。共进行了26次手术,其中6例使用了术后放疗。足底筋膜切除术的复发率最低。在显微镜下切除不完全或仅切除早期复发(≤6个月)的所有肿瘤均复发,而辅助放疗后很少观察到复发。然而,有3例放疗与功能结局明显受损有关。
足底纤维瘤病相对罕见。足底筋膜切除术似乎是首选手术方式。辅助放疗虽然在降低复发率方面有效,但由于其严重的副作用,应非常有选择性地使用。