Agerbo Esben, Byrne Majella, Eaton William W, Mortensen Preben B
National Centre for Register-Based Research, University of Aarhus, Taasingegade 1, Aarhus 8000 C, Denmark.
Arch Gen Psychiatry. 2004 Jan;61(1):28-33. doi: 10.1001/archpsyc.61.1.28.
Singleness and unemployment increase the risk of schizophrenia. Schizophrenia subsequently increases the risk of singleness and unemployment.
To describe long-term changes in marital status and labor market affiliation before and after the first admission with schizophrenia.
A case-control study.
The sample included 5341 patients with a diagnosis of schizophrenia at the first admission to a psychiatric facility between 1970 and 1999, and 53 410 matched control subjects. A person admitted in 1999 was followed up in the registers from 1980 to 1997 (ie, from 19 to 2 years before admission). Individuals admitted in 1970 could be followed up from 10 years until 27 years after admission.
Annual socioeconomic indicators.
Individuals who were later hospitalized were more frequently living alone, unemployed, receiving social benefits, or otherwise outside the labor market when compared with controls, as early as 19 years before their first admission. For individuals with schizophrenia, the odds ratios of being unmarried or not being fully employed were significantly increased even 25 years after admission. This pattern was especially pronounced for men and for individuals who had more admissions. The ratios increased until admission, with a steeper increase in the years before admission. After admission, the odds declined to the level shown before admission and then stabilized.
Schizophrenia hinders social achievement long before the first admission. The first hospital episode is followed by a period during which social status does not deteriorate further except for the transition into disability pension.
单身和失业会增加患精神分裂症的风险。而精神分裂症反过来又会增加单身和失业的风险。
描述首次因精神分裂症入院前后婚姻状况和劳动力市场归属的长期变化。
一项病例对照研究。
样本包括1970年至1999年间首次入住精神病院且诊断为精神分裂症的5341名患者,以及53410名匹配的对照对象。1999年入院的患者从1980年至1997年(即入院前19至2年)在登记册中进行随访。1970年入院的个体可在入院后10年至27年进行随访。
年度社会经济指标。
与对照组相比,后来住院的个体早在首次入院前19年就更频繁地独居、失业、领取社会福利或以其他方式脱离劳动力市场。对于精神分裂症患者,即使在入院25年后,未婚或未充分就业的比值比也显著增加。这种模式在男性和入院次数较多的个体中尤为明显。比值在入院前不断增加,入院前几年增加得更快。入院后,比值降至入院前所示水平,然后趋于稳定。
精神分裂症在首次入院前很久就会阻碍社会成就。首次住院后会有一段时间,除了转为残疾抚恤金外,社会地位不会进一步恶化。