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精神疾病和劳动力市场状况对自杀的影响:健康工人效应?

Effect of psychiatric illness and labour market status on suicide: a healthy worker effect?

作者信息

Agerbo Esben

机构信息

National Centre for Register-based Research, University of Aarhus, DK-8000 Aarhus C, Denmark.

出版信息

J Epidemiol Community Health. 2005 Jul;59(7):598-602. doi: 10.1136/jech.2004.025288.

Abstract

STUDY OBJECTIVE

To describe the association between labour market status and death by suicide with focus on admission with a psychiatric disorder.

DESIGN

Nested case-control study. Data from routine registers.

SETTING

Entire Danish population.

PARTICIPANTS

9011 people aged 25-60 years who committed suicide during 1982-1997 and 180 220 matched controls.

MAIN RESULTS

In the general population, not being fully employed is associated with a twofold to threefold increased relative risk of death by suicide, compared with being fully employed. In contrast, fully employed people who have been first admitted to a psychiatric hospital within the past year are at increased suicide risk. Patients who are unemployed, social benefits recipients, disability pensioners, or otherwise marginalised on the labour market have a suicide risk of 0.60 (95% CI: 0.46 to 0.78), 0.41 (0.23 to 0.74), 0.70 (0.45 to 1.08), and 0.86 (0.53 to 1.41), respectively. Although a similar risk decrease is found in women, men, people younger than 30 years, people older than 45 years, and in people who become unemployed, the reversed effect attenuates with time since admission, and little association is seen when a marginal structural model is applied.

CONCLUSIONS

Although the results show an increased suicide mortality associated with unemployment and labour market marginalisation in the general population, the results suggest little or an inverse association between unemployment and suicide in people with psychiatric illness. The associations seen suggest the need to consider healthy worker selection effects when studying the causal pathway from unemployment and psychiatric illness to suicide.

摘要

研究目的

描述劳动力市场状况与自杀死亡之间的关联,重点关注因精神疾病入院的情况。

设计

嵌套病例对照研究。数据来自常规登记册。

研究地点

丹麦全体人口。

研究对象

1982年至1997年间自杀的9011名25至60岁的人和180220名匹配的对照者。

主要结果

在普通人群中,与充分就业者相比,未充分就业者自杀死亡的相对风险增加了两倍至三倍。相比之下,在过去一年内首次入住精神病院的充分就业者自杀风险增加。失业者、领取社会福利者、残疾养老金领取者或以其他方式在劳动力市场上处于边缘地位的患者自杀风险分别为0.60(95%置信区间:0.46至0.78)、0.41(0.23至0.74)、0.70(0.45至1.08)和0.86(0.53至1.41)。尽管在女性、男性、30岁以下人群、45岁以上人群以及失业人群中发现了类似的风险降低情况,但这种相反的效应会随着入院时间的推移而减弱,并且在应用边缘结构模型时几乎没有发现关联。

结论

尽管结果显示普通人群中与失业和劳动力市场边缘化相关的自杀死亡率有所增加,但结果表明精神疾病患者中失业与自杀之间几乎没有关联或存在负相关。所观察到的关联表明,在研究从失业和精神疾病到自杀的因果途径时,需要考虑健康工人选择效应。

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