Paquier P, van Mourik M, van Dongen H, Catsman-Berrevoets C, Brison A
Services de Neurologie et de Neuropsychologie, Hôpital Universitaire Erasme ULB, Bruxelles, Belgique.
Rev Neurol (Paris). 2003 Nov;159(11):1017-27.
Cerebellar mutism and subsequent dysarthria (MSD) is a possible complication of posterior fossa surgery. It is usually seen in children after resection of a cerebellar mass lesion. Most patients become mute after a period of (near)normal postoperative speech, and are dysarthric once speech resumes. The pathophysiological mechanisms underlying MSD are most probably multifactorial, combining neuroanatomical, neurophysiological, neuropsychological, and psychological factors. The aim of the present article is to better define the MSD syndrome. The cerebellum is not only involved in motor control. It is also part of a distributed neural circuitry which underlies higher cognitive functions such as, for instance, those associated with the programming of kinetic parameters before motor initiation of a movement. We hypothesize that it could also be involved in the mental initiation which precedes the programming of any intentional bucco-phonatory movements to be performed in order to express oneself.
小脑缄默症及随后的构音障碍（MSD）是后颅窝手术可能出现的并发症。它通常见于儿童小脑肿块病变切除术后。大多数患者在术后一段时间（接近）正常言语后变得缄默，恢复言语后出现构音障碍。MSD潜在的病理生理机制很可能是多因素的，涉及神经解剖学、神经生理学、神经心理学和心理学因素。本文旨在更明确地界定MSD综合征。小脑不仅参与运动控制。它也是一个分布式神经回路的一部分，该神经回路是更高认知功能的基础，例如与运动开始前动力学参数编程相关的功能。我们推测，它也可能参与在为表达自己而进行任何有意的口部发声运动编程之前的心理启动过程。
